Interdisciplinary Conference of Young Scholars in Social Sciences (USA)

The Effect of Emotional and Nervous Changes in the Body on Acne in Patients With Functional Dyspepsia

Akramova Nodira Shuxratovna

Bukhara State Medical Institute Named After Abu Ali Ibn Sina

Abstract

Acute and chronic stress, as a powerful etiological factor of PD, is an integral part of inflammatory skin lesions, where lipid peroxidation is activated, microcirculation is disrupted. It is generally believed that the pathological process in the mucous membrane of the stomach and duodenum is accompanied by autoimmune reactions that lead to inflammatory skin lesions. Among the etiological factors of these diseases, special attention is currently being paid to Helicobacter pylori (Hp), which is the cause of it in 96-100% of cases. Thus, the most significant etiological factors in the development of lesions of the mucous membrane (CO) of the gastrointestinal tract (gastrointestinal tract) are H. pylori infection (associated with it - PD, chronic gastritis, peptic ulcer and other diseases).

Traditionally, with this pathology, the patient is prescribed antibiotics, sometimes the unannounced intake of these pharmaceuticals leads to increased activity of oxidative enzymes of the existing microflora, leading to damage to the integrity of the gastric mucosa, up to pronounced excvation of the epithelial layer. It was revealed that the wall of Helicobacter pylori (Hp) has pathogenic properties due to the presence of a specific CagA protein, this protein is in fact one of the "initiators" of the production of pro-inflammatory cytokines, in particular interleukin-8 (IL-8). This dictates the requirement to strictly follow treatment protocols, including eradication of helicobacter infection.