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2023-02-18
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Modern Diagnosis of Medicine-Induced GI Bleeding From the Gastrointestinal System
Xamroev Baxtiyor Sultonovich
Bukhara State Medical Institute Named Abu Ali Ibn Sino Bukhara Branch of the Scientific Center of Emergency Medical Aid of the Republic
Abstract
All non-steroidal anti-inflammatory drugs or drugs that block cyclooxygenase-1 reduce the function of prostaglandins, reduce the protective properties of the mucosa by increasing the gastric hypersecretion and the acidopeptic and aggressive activity of gastric juice, which in turn leads to the violation of the integrity of the mucous membranes of the stomach and duodenum and to this pathological condition. causes the process to continue chronically. It is also worth noting that long-term use of NSAIDs and risk factors that cause erosion or ulcers in the mucous membrane of the stomach and duodenum should also be taken into account. Vyalov SS, Zimmerman JA, Sigano K, Tack J, Kuipers EJ. 2012. Currently, bleeding due to gastric and duodenal ulcers has doubled, especially in the elderly and elderly. The death rate from acute bleeding due to wounds from the gastrointestinal system is 4-20%, after emergency operations it is 4-73%, and in the elderly this rate is 80% higher (Denisov I.N., Shavkuta D.M., Sajin V.P. ., Savelev V.M., Sajin I.V., Khadjibaev A.M.).
