Formation and Development of Pedagogical Creativity: International Scientific-Practical Conference (Belgium)

Lipoperoxidation Syndrome and Liver Dysfunction in Rhinosinusitis with Comorbidity and Chronic Obstructive Pulmonary Disease

Saliakhunova X. O. — 2024-11-08

Studying the semantic field of “ma’naviyat” and its descriptive meanings in different dictionaries written from 1981 till the present time has been analysed in this article. The works carried out on the similar topics are also discussed and their differences are analyzed.

Assessment of the Effect of Anemia on the Clinical Status, Mobile Activity and Quality of Life in Patients with Ckd

Naimova Sh. A. — 2024-11-08

Chronic kidney disease (CKD) is a progressive condition marked by the gradual loss of kidney function over time. Among the numerous complications that accompany CKD, anemia is one of the most prevalent and impactful. This condition arises primarily due to a deficiency in erythropoietin production by the damaged kidneys, compounded by iron deficiency and shortened red blood cell lifespan. Understanding the effects of anemia in CKD patients is crucial as it significantly affects their clinical status, mobile activity, and overall quality of life.

The Prognostic Significance of Hepcidin, VEGF, Transferrin Receptor, and Cytokines in the Pathogenetic Diagnosis of Anemia in Patients with RA and CKD Together

Naimova Sh. A. — 2024-11-08

Anemia is a common complication in patients suffering from both rheumatoid arthritis (RA) and chronic kidney disease (CKD). The coexistence of these conditions compounds the complexity of anemia's pathogenesis, necessitating advanced diagnostic and prognostic approaches. Among the biomarkers gaining attention for their potential roles in understanding and managing anemia in these patients are hepcidin, vascular endothelial growth factor (VEGF), transferrin receptor, and various cytokines. Anemia is a frequent complication in patients with both rheumatoid arthritis (RA) and chronic kidney disease (CKD). While traditional markers like hemoglobin and ferritin are used to diagnose anemia, they often fail to capture the complex pathophysiological mechanisms underlying this condition. Recent research has highlighted the role of specific biomarkers, including hepcidin, vascular endothelial growth factor (VEGF), transferrin receptor (TfR), and inflammatory cytokines, in the development and progression of anemia in these patient populations. Hepcidin: A Key Regulator of Iron Homeostasis Hepcidin, a liver-derived peptide hormone, plays a crucial role in iron homeostasis by regulating iron absorption from the gut and iron release from stores. In inflammatory conditions like RA and CKD, elevated levels of inflammatory cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), stimulate hepcidin production. Increased hepcidin levels lead to decreased iron absorption and release, contributing to iron deficiency anemia.

Organizational Pedagogical Directions in the Management of the Education System in Higher Education Institutions

Esanova Aziza — 2024-11-08

Organizational pedagogical directions in the management of the education system in higher education institutions refer to the strategies, principles, and practices that guide the educational processes and the administration of learning environments in universities and colleges. Here are several key directions that can be considered:

Modern Methods of Working with Students in Higher Educational Institutions of the United States of America

Esanova Aziza — 2024-11-08

Modern methods of working with students in U.S. higher educational institutions emphasize adaptability, engagement, and inclusivity. Below is an overview of several key strategies currently shaping student-centered approaches in the U.S., along with some references for further reading.

Disabled Children in Inclusive Education, Problems in Teaching and Education

Roziboyeva Ma'murakhan Abdunabiyevna — 2024-11-11

In this article, we described the problems of introducing inclusive education in educational institutions in Uzbekistan. We have studied and described the following psychological problems. The pace of learning and the amount of knowledge, because it is difficult for children with disabilities to study at the prescribed pace in non-specialized correctional institutions. The problem considered and described is the establishment of psychological relationships between children with disabilities and healthy children.